Christian G Bien Selected Research

Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)

7/2020	Routine diagnostics for neural antibodies, clinical correlates, treatment and functional outcome.
1/2017	Selective Limbic Blood-Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies.
5/2014	IgG and complement deposition and neuronal loss in cats and humans with epilepsy and voltage-gated potassium channel complex antibodies.
8/2012	Febrile infection-related epilepsy syndrome without detectable autoantibodies and response to immunotherapy: a case series and discussion of epileptogenesis in FIRES.
5/2012	Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis.
5/2012	Epileptic encephalitis: the role of the innate and adaptive immune system.
8/2011	Autoantibodies associated with diseases of the CNS: new developments and future challenges.
4/2011	Autoimmune epilepsies.
6/2006	Serial MRI of limbic encephalitis.
3/2004	Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis.

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Christian G Bien Research Topics

Disease

37	Epilepsy (Aura) 03/2022 - 08/2002
28	Encephalitis (Encephalitis, Rasmussen) 01/2022 - 03/2008
26	Seizures (Absence Seizure) 06/2022 - 09/2005
13	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) 03/2022 - 03/2004
12	Autoimmune Diseases of the Nervous System 01/2022 - 01/2013
12	Glioma (Gliomas) 01/2022 - 08/2012
9	Temporal Lobe Epilepsy 01/2022 - 04/2010
9	Brain Diseases (Brain Disorder) 01/2020 - 03/2004
6	Neoplasms (Cancer) 01/2021 - 06/2006
5	Partial Epilepsies (Epilepsy, Partial) 01/2021 - 08/2014
5	Hippocampal Sclerosis 10/2017 - 03/2009
4	Inflammation (Inflammations) 10/2021 - 06/2006
4	Drug Resistant Epilepsy 01/2021 - 03/2013
4	Anti-N-Methyl-D-Aspartate Receptor Encephalitis 01/2018 - 01/2012
3	Stiff-Person Syndrome (Stiff Man Syndrome) 03/2022 - 08/2014
3	Ataxia (Dyssynergia) 03/2022 - 01/2016
3	Tuberous Sclerosis (Bourneville's Disease) 01/2021 - 07/2011
3	Epileptic Syndromes 01/2021 - 04/2011
3	Nervous System Diseases (Neurological Disorders) 02/2020 - 08/2015
3	Focal Cortical Dysplasia 10/2017 - 07/2007
3	Myoclonus (Nocturnal Myoclonus) 12/2015 - 03/2008
3	Epilepsia Partialis Continua 12/2015 - 03/2008
2	Genetic Predisposition to Disease (Genetic Predisposition) 03/2022 - 01/2019
2	Autoimmune limbic encephalitis 01/2022 - 01/2017
2	Headache (Headaches) 10/2021 - 08/2014
2	Febrile Seizures (Febrile Seizure) 01/2021 - 12/2010
2	Paresis (Hemiparesis) 01/2020 - 08/2002
2	Cognitive Dysfunction 01/2018 - 01/2011
2	Movement Disorders (Movement Disorder) 12/2015 - 03/2008
2	Atrophy 05/2012 - 04/2012
2	Status Epilepticus (Complex Partial Status Epilepticus) 01/2012 - 03/2008
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2022
1	Oligodendroglioma 01/2022
1	COVID-19 10/2021
1	Psychotic Disorders (Schizoaffective Disorder) 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Neurologic Manifestations (Neurological Manifestations) 12/2020
1	Cerebellar Diseases (Cerebellar Syndrome) 12/2020
1	Neuralgia (Stump Neuralgia) 01/2020
1	Autonomic Nervous System Diseases (Dysautonomia) 01/2020
1	Isaacs Syndrome (Neuromyotonia) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 01/2020
1	Viral Encephalitis 10/2017

Drug/Important Bio-Agent (IBA)

48	AntibodiesIBA 01/2022 - 03/2004
19	AutoantibodiesIBA 03/2022 - 09/2005
16	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2021 - 04/2009
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2012
13	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 03/2022 - 04/2010
12	Leucine (L-Leucine)FDA Link 01/2022 - 05/2013
10	AntigensIBA 03/2021 - 05/2012
10	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 07/2020 - 03/2004
10	Anticonvulsants (Antiepileptic Drugs)IBA 01/2020 - 08/2009
6	Pharmaceutical PreparationsIBA 01/2021 - 11/2006
5	Complement System Proteins (Complement)IBA 01/2018 - 05/2012
4	Surface Antigens (Surface Antigen)IBA 03/2021 - 05/2011
4	Lacosamide FDA Link 01/2021 - 07/2015
4	Immunoglobulin G (IgG)IBA 12/2020 - 05/2014
4	N-Methylaspartate (NMDA)IBA 03/2016 - 06/2010
4	Potassium Channels (Potassium Channel)IBA 03/2016 - 03/2004
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 08/2009
3	Aminobutyrates (Aminobutyric Acid)IBA 01/2022 - 03/2016
3	Glycine Receptors (Glycine Receptor)IBA 01/2021 - 08/2011
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2021 - 08/2009
3	trans-sodium crocetinate (crocetin)IBA 01/2021 - 07/2011
3	AMPA Receptors (AMPA Receptor)IBA 03/2016 - 04/2011
2	Levetiracetam (Keppra)FDA LinkGeneric 06/2022 - 01/2021
2	Protein Isoforms (Isoforms)IBA 03/2022 - 01/2022
2	N 30IBA 01/2021 - 12/2020
2	Rituximab (Mabthera)FDA Link 01/2021 - 08/2009
2	AcidsIBA 01/2021 - 08/2012
2	metabotropic glutamate receptor type 1IBA 12/2020 - 11/2020
2	brivaracetamIBA 01/2020 - 11/2016
2	anti-leucine-rich glioma-inactivated 1 autoantibodyIBA 01/2018 - 01/2017
2	Biomarkers (Surrogate Marker)IBA 04/2016 - 02/2014
2	TOR Serine-Threonine KinasesIBA 01/2016 - 02/2015
2	erucylphosphocholineIBA 12/2015 - 03/2008
2	Tacrolimus (Prograf)FDA LinkGeneric 03/2013 - 08/2009
2	SteroidsIBA 01/2013 - 03/2008
2	GABA-B ReceptorsIBA 08/2012 - 08/2011
2	Glutamate Receptors (Glutamate Receptor)IBA 08/2012 - 06/2010
2	gamma-Aminobutyric Acid (GABA)IBA 08/2012 - 08/2011
2	Oligoclonal BandsIBA 01/2012 - 06/2010
1	HLA Antigens (Human Leukocyte Antigens)IBA 03/2022
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2022
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2022
1	Methylprednisolone FDA LinkGeneric 10/2021
1	Antipsychotic Agents (Antipsychotics)IBA 01/2021
1	Lamotrigine (Lamictal)FDA LinkGeneric 01/2021
1	Polytetrafluoroethylene (Teflon)FDA Link 01/2021
1	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 12/2020
1	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 10/2020
1	EnzymesIBA 02/2020
1	adenylate kinase 5IBA 01/2019
1	SodiumIBA 01/2018
1	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 12/2017

Therapy/Procedure

12	Immunotherapy 01/2018 - 03/2004
7	Therapeutics 01/2019 - 01/2013
3	Electrodes (Electrode) 09/2021 - 01/2011
2	Drug Therapy (Chemotherapy) 01/2022 - 08/2002
2	Hemispherectomy 02/2014 - 03/2013